Spotlight On: Serpin B3 Inhibitor and the Shiseido Future Solution LX Line

By Nicki Zevola — December 19, 2009

Every time you turn around, it seems a skin care company is proposing a new technology to improve the look and feel of your skin.  Shiseido’s new Future Solution LX Line ($248.85 discount, Amazon.com) is amongst the latest, proposing that its Serpin B3 inhibitor will “intensively energize your skin” and “reduce all signs of aging.”  Hm.  Is this line all it declares itself to be?  FutureDerm investigates…

Skingenecell 1P, a Serpin B3 Inhibitor:  Exciting Stuff

According to the Journal of Allergy and Clinical Dermatology, the skin’s levels of serpin B3 are elevated in patients with dry and damaged skin.  When serpin B3 levels are reduced, the skin restores its moisture levels and prior smoothness.  What’s more is that serpin B3 levels are slightly elevated in cancerous cells and in psoriatic skin cells, encouraging further interest in a serpin B3 inhibitor.

Enter Shiseido’s patented synthetic amino acid, Skingenecell 1P, which has been proven in Shiseido’s in-house studies to significantly reduce the amount of serpin B3 in skin cells.  This, in direct correlation to the in vitro (i.e., petri dish-like) studies, should in fact directly help to restore dry and UV-damaged skin to levels of higher moisture and increased smoothness.

And I’m not the only one excited about serpin B3 inhibitor.  As Ava Shamban, assistant clinical professor of dermatology at UCLA, tells Judith Newman in this month’s Allure: “[Skingenecell 1P] is a very interesting approach…Most companies are adding proteins or lipids that our bodies produce already, to supplement our natural moisture content.  This is a new compound Shiseido has generated that fights a damaging substance in our body so that it addresses the decrease in moisture from the inside out.  It’s able to restore normal moisture levels.”

Things to Consider

One thing to keep in mind when considering the Future Solution LX Line is the current state of your skin.  If you have dry to very dry skin, visible UV damage, live in a warm climate, and are 40 or older (all parameters associated with increased serpin B3 levels), then the Future Solution LX Line is most likely to benefit you.  However, if you simply have dry skin and no visible UV damage, you may benefit similarly from a more basic moisturizer.

If you decide to purchase only one product from this line to start, make it the Shiseido Future Solution Total Regenerating Cream, as prior experience with Shiseido has taught me that this company tends to put the highest concentration of active ingredients in their night moisturizers.

The truth is that I’m thrilled with the technology behind the new Future Solution LX Line , and I’m proud to be able to present this type of exciting advancement to my readers!  Let me know your thoughts in Comments below!  :-)

Picture 8

pixelstats trackingpixel

About Author

Founder and CEO Nicki Zevola started FutureDerm as a medical (M.D.) student studying to be a dermatologist. She is an award-winning scientific researcher and writer. She currently is concentrating on FutureDerm and developing FutureDerm's one-of-a-kind products. She can be found on and Twitter.

View all Nicki Zevola posts.

(10) Readers Comments

  1. Kathleen
    December 19, 2009 at 3:35 am

    This cream is luxurious; feels great when applying and left me well-moisturized in the morning (and I live in the desert), However, I developed millia while using and would not consider using FS again.

  2. Ruben
    December 20, 2009 at 8:18 pm

    I once gave my professor some products including Shiseido’s to reseach them with the Infrared lights and she said that Shiseido products ar worth nothing when it comes to amounts of active ingredients, concentration was utterly low. shame if you consider the price

  3. Karlo
    December 21, 2009 at 4:38 pm

    To Ruben
    Could you be so kind and informed us about other products you gave to your professor which had low amount of active ingredients?

  4. December 23, 2009 at 7:08 am

    I totally agree with Karlo.

    Believed it will benefit many others if you could provide us with the products you gave your Prof. for testing so that we will know what these actually are.

    As a reputable and historically rich company like Shiseido, they may too sometimes as with many other big wigs companies out there, do have some mistakes with their range launched but even so, may not necessary be applicable to each and every product of theirs.

  5. Jen
    December 23, 2009 at 12:43 pm

    Loved your blog. Readers might also be interested in another article I found, about beauty and dry eyes. It can be found here at this website:

    http://whatistheeye.wordpress.com/

  6. December 29, 2009 at 6:25 pm

    Just the fact that there is jar packaging involved is a HUGE red flag for these products. None of the active ingredients that they claim to include in the products would remain stable after opening!

  7. cloe
    September 2, 2010 at 11:17 am

    I am using this for 1 month now but it seems no improvement on my skin. I will continue for a few weeeks more to see if it will really works coz if not, i will waste huge amount of money for buying the complete line of future solution lx

  8. ELLEN MOORE
    January 28, 2011 at 11:47 pm

    I am a Shiseido counter manager in Chicago. I have clients that are seeing remarkable results. I have a client 40 who is Chinese she started with Future Sol LX and used it up and her friend told her to try Chanels top products which she did. She changed nothing in her lifestyle. All of a sudden she got brown spots on her face and came to see me. I asked her life style etc health on so on. Come to find out the sun just from normal going outside caused her these spots. You see when she was using the Future LX she was protected from skin damage because of the skingenecell1P supressing the serpen b3 as it is a natural sun block if you will. I have studied these products and all of the ingredients and can tell you there is nothing like it on the market anywhere. My cleints look younger by the week from these products I cant even keep them in stock.

  9. Caryn
    September 23, 2011 at 11:20 am

    How does this treatment compare with DIOR SNOW DNA? I agree the night treatments on most lines has the strongest active product.
    I love this website for all the truth in skincare treatments.

  10. Pingback: Shiseido Lança Vídeo Mostrando seu Investimento em Pesquisa e Densevolvimento | East to West Skin Care

Leave A Reply

Leave a Reply

Your email address will not be published. Required fields are marked *

You may use these HTML tags and attributes: <a href="" title=""> <abbr title=""> <acronym title=""> <b> <blockquote cite=""> <cite> <code> <del datetime=""> <em> <i> <q cite=""> <strike> <strong>

FutureDerm Retinol

AqualantAd209x209

Youth Superfoods

Subscribe & Save

Subscribe to our RSS Feed

Get emails about new posts, contests and reviews.

Other Sponsors

Calendar

December 2009
M T W T F S S
« Nov   Jan »
 123456
78910111213
14151617181920
21222324252627
28293031  

Disclaimer

Please note: This site is only for informative purposes. It is not intended to be a substitute for professional medical advice. Please consult your doctor for your medical concerns. The author is not liable for any outcome or damage resulting from information obtained from this site.