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Spotlight On: Serpin B3 Inhibitor and the Shiseido Future Solution LX Line

Every time you turn around, it seems a skin care company is proposing a new technology to improve the look and feel of your skin.  Shiseido's new Future Solution LX Line ($248.85 discount, is amongst the latest, proposing that its Serpin B3 inhibitor will "intensively energize your skin" and "reduce all signs of aging."  Hm.  Is this line all it declares itself to be?  FutureDerm investigates...

Skingenecell 1P, a Serpin B3 Inhibitor:  Exciting Stuff

According to the Journal of Allergy and Clinical Dermatology, the skin's levels of serpin B3 are elevated in patients with dry and damaged skin.  When serpin B3 levels are reduced, the skin restores its moisture levels and prior smoothness.  What's more is that serpin B3 levels are slightly elevated in cancerous cells and in psoriatic skin cells, encouraging further interest in a serpin B3 inhibitor. Enter Shiseido's patented synthetic amino acid, Skingenecell 1P, which has been proven in Shiseido's in-house studies to significantly reduce the amount of serpin B3 in skin cells.  This, in direct correlation to the in vitro (i.e., petri dish-like) studies, should in fact directly help to restore dry and UV-damaged skin to levels of higher moisture and increased smoothness. And I'm not the only one excited about serpin B3 inhibitor.  As Ava Shamban, assistant clinical professor of dermatology at UCLA, tells Judith Newman in this month's Allure: "[Skingenecell 1P] is a very interesting approach...Most companies are adding proteins or lipids that our bodies produce already, to supplement our natural moisture content.  This is a new compound Shiseido has generated that fights a damaging substance in our body so that it addresses the decrease in moisture from the inside out.  It's able to restore normal moisture levels."

Things to Consider

One thing to keep in mind when considering the Future Solution LX Line is the current state of your skin.  If you have dry to very dry skin, visible UV damage, live in a warm climate, and are 40 or older (all parameters associated with increased serpin B3 levels), then the Future Solution LX Line is most likely to benefit you.  However, if you simply have dry skin and no visible UV damage, you may benefit similarly from a more basic moisturizer. If you decide to purchase only one product from this line to start, make it the Shiseido Future Solution Total Regenerating Cream, as prior experience with Shiseido has taught me that this company tends to put the highest concentration of active ingredients in their night moisturizers. The truth is that I'm thrilled with the technology behind the new Future Solution LX Line , and I'm proud to be able to present this type of exciting advancement to my readers!  Let me know your thoughts in Comments below!  :-) Picture 8