Coenzyme Q-10: Antioxidant and Anti-inflammatory Action
Coenzyme Q-10 — also known as ubiquinone — is found naturally in the human body as something essential for the production of cells (Mayo Clinic). Coenzyme Q-10 levels are at their highest for the first 20 years of life and then subsequently decrease as we age. Researchers are investigating how this antioxidant might be related to the aging process and longer life span. Though it’s shown process with lab rats, it doesn’t appear to do much for lab rats (MedlinePlus).
Coenzyme Q-10 is considered a regenerative antioxidant (Journal of the American College of Nutrition). When applied to the skin, Coenzyme Q-10 has been shown to penetrate the skin layers and reduce the oxidation, reduce wrinkles, and prevent UVA-irradiation damage (Biofactors). It’s antioxidant and coenzyme effects also help prevent cell death.
Q-10 is an integral part of the mitochondrial electron transport chain, which is depolarized by UVB-irradiation. When skin was treated with Q-10 before UVB exposure, it mitigated these effects and increased cell viability (Journal of Biological Chemistry).
In addition to this, Coenzyme Q-10 helps to suppress the inflammation that occurs with UV-irradiation. That was magnified when coenzyme Q-10 was applied with carotenoids like beta-carotene (Journal of Cosmetic Dermatology). When mixed with carotenoids, it’s also able to stop the UVR induction of matrix metalloproteinase-1, which degrade collagen (Journal of Cosmetic Dermatology). In this way it serves as a powerful ingredient in anti-aging.
Coenzyme Q-10 can degrade in heat and light, so products in air tight, opaque containers are ideal (Chemical Pharmacy Bulliten).
Coenzyme Q10 Works Together with Vitamin C and Vitamin E
As longtime FutureDerm readers know, different antioxidants work on different pathways within the skin. There are at least three major pathways that detoxify the skin (as well as the rest of your cells) from free radicals (Nature, 2013).
What makes coenzyme Q10 great for use with vitamin C as L-ascorbic acid and vitamin E is that it operates in the same pathway as these antioxidants. This means that, when any of the three antioxidants encounter a free radical and neutralize it, losing an electron in the process, they can be regenerated by having one of the other two antioxidants donate an electron (Cosmetic Dermatology). For this reason, coenzyme Q10-containing products are a great addition to use with vitamin C + vitamin E-containing products, like our FutureDerm Vitamin CE Caffeic Serum.
Chia Seed: Is There Any Known Benefit for the Skin?
Chia seed is a natural source of omega-3 fatty acids (Poultry Science, 2002), which are anti-inflammatory fatty acids naturally found within the skin. Omega-3 fatty acids are documented to be substantially lower in those with dry/very dry skin types than those with normal to oily skin types, though omega-3 supplementation (whether oral or topical) can help this, returning skin to a more youthful, supple state.
Topical chia seed oil has also been documented in the journal Annals of Dermatology to relieve severe symptoms of pruritus, or skin itching.
Overall, is chia seed oil going to remove your fine lines and wrinkles? Fix hyperpigmentation? Encourage collagen production? Answer: Probably not; no; almost certainly no. But, if you suffer from dry to very dry skin, chia seed oil is likely to temporarily plump up your skin, reducing the appearance of fine lines somewhat.
Coenzyme Q-10 has beneficial effects in and on the body and hasn’t been found to have many negative reactions, though it is as of yet untested on pregnant women and children. Some think it could help people live longer because it’s in every cell and is an integral part of cell production. On skin, it’s a powerful antioxidant and excellent for anti-aging, and works particularly well in conjunction with vitamin C as L-ascorbic acid and vitamin E.
What are your thoughts on Coenzyme Q10? Let’s discuss in Comments below!
Ingredients in Perricone MD Chia Serum
Limnanthes Alba (Meadowfoam) Seed Oil, Aleurites Moluccana Seed Oil, Oryza Sativa (Rice) Bran Oil, Salvia Hispanica Seed Oil, Retinyl Palmitate, Zea Mays (Corn) Oil, Tetrahexyldecyl Ascorbate, Ubiquinone, Elaeis Guineensis (Palm) Oil, Panthenol, Tocotrienols, Tocopherol, Fragrance.