I’ve seen a lot of products with Saccharomyces ferment lysate in them recently. Does it have any effect?
There are some who believe yeast (Saccharomyces) may stimulate DNA repair in the skin. This is based on the fact yeast contains a sequence of DNA that is necessary for double-strand DNA break repair, a major finding that was published in the highly acclaimed journal Nature in 2000.
However, topical application of yeast has never been shown to promote DNA repair. The DNA motif within yeast would have to penetrate through the cell membrane, cytoplasm, and nuclei to reach the DNA within skin cells, and this simply is not likely.
Furthermore, even if yeast could reach our DNA, it wouldn’t be doing anything new. Scientists love yeast because its genes are well-sequenced and relatively easy to manipulate, but its repair genes are similar to the ERCC1 repair genes already found within the human genome, according to the Annual Review of Genetics.
There is limited research to suggest yeast may stimulate wound healing or act as an antioxidant. Yeast also is an antioxidant and a reasonable source of B vitamins. So it’s not to say yeast is detrimental to the skin. It’s just not likely the DNA from topically applied yeast is reaching our own inner cell machinery. And even if it did, the yeast genes introduced are nothing novel, as they are very similar to the DNA repair genes naturally occurring within the skin.
Products Containing Yeast
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