Bakuchiol

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Bakuchiol (Wikipedia)
Bakuchiol
Chemical structure of bakuchiol
Names
IUPAC name
4-[(1E,3S)-3-ethenyl-3,7-dimethylocta-1,6-dienyl]phenol
Other names
(+)-Bakuchiol
Identifiers
10309-37-2 N=
ChEMBL ChEMBL262344 YesY
ChemSpider 4579217 YesY
Jmol 3D image Interactive graph
PubChem 5468522
UNII OT12HJU3AR YesY
Properties
C18H24O
Molar mass 256.38 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YesYN ?)
Infobox references

Bakuchiol is a meroterpene (a chemical compound having a partial terpenoid structure) in the class terpenophenol. It is found in Psoralea corylifolia and in Otholobium pubescens.

It has been reported to have anticancer activity in pre-clinical models, possibly due to its structural similarity with resveratrol. One study in rats suggested that bakuchiol and ethanol extracts of the Chinese medicinal plant Psoralea corylifolia could protect against bone loss. Bakuchiol isolated from P. corylifolia has shown activity against numerous Gram-positive and Gram-negative oral pathogens. It was able to inhibit the growth of Streptococcus mutans under a range of sucrose concentrations, pH values and in the presence of organic acids in a temperature-dependent manner and also inhibited the growth of cells adhered to a glass surface.

Bakuchiol was also found to have retinol functionality.

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