An excellent natural moisturizing factor that improves skin barrier function. It binds water to the skin and promotes the production of keratin.
Carbamide, carbonyl diamide, carbonyldiamine, diaminomethanal, diaminomethanone
|Jmol 3D image||Interactive graph|
|Molar mass||60.06 g·mol−1|
|Melting point||133 to 135 °C (271 to 275 °F; 406 to 408 K)|
|1079 g/L (20 °C)
1670 g/L (40 °C)
2510 g/L (60 °C)
4000 g/L (80 °C)
|Solubility||500 g/L glycerol, 50g/L ethanol|
|Basicity (pKb)||pKBH+ = 0.18|
|B05BC02 (WHO) D02|
|Safety data sheet||JT Baker|
|Lethal dose or concentration (LD, LC):|
LD50 (Median dose)
|8500 mg/kg (oral, rat)|
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
|what is ?)(|
Urea serves an important role in the metabolism of nitrogen-containing compounds by animals, and is the main nitrogen-containing substance in the urine of mammals. It is a colorless, odorless solid, highly soluble in water, and practically non-toxic (LD50 is 15 g/kg for rats). Dissolved in water, it is neither acidic nor alkaline. The body uses it in many processes, most notably nitrogen excretion. The liver forms it by combining two ammonia molecules (NH3) with a carbon dioxide (CO2) molecule in the urea cycle. Urea is widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry.
Friedrich Wöhler's discovery in 1828 that urea can be produced from inorganic starting materials was an important conceptual milestone in chemistry. It showed for the first time that a substance previously known only as a byproduct of life could be synthesized in the laboratory without biological starting materials, contradicting the widely held doctrine of vitalism.