Product Review: Age Advantage Wrinkle Reduction Creme

Reviews, Skin Care
I like Age Advantage Wrinkle Reduction Creme, primarily due to the glycolic acid and the superior antioxidant combination (i.e., vitamin E, alpha lipoic acid, and ubiquinone).

Recently, a gentleman from a company e-mailed me.  He said his name was Andrew, and he worked for a company called Age Advantage.  He sent info and photos about his products, and offered a sample.

Being a blogger, I’m very fortunate to get e-mails like this all the time.  But what set Andrew apart was that he actually called to follow up.  It reminded me of a business interaction from another time:  How did I like the products?  What could he do to help me?  Did I need more information for the review?

They say that dogs look a little like their owners.  Well, I’ve found that skin care products tend to resemble their developers.  And in this case, Andrew’s products reminded me of him:  unique; brazen; and, truth be told, a little bit from another time.  (The packaging reminds me a little bit of the 80’s or 90’s).  But the science behind them struck a chord with me, just like the manners of someone who takes the time to make a phone call in this day and age.

So, with that said, here is the science behind my favorite Age Advantage product, Age Advantage Wrinkle Reduction Creme ($64.98,

Glycolic Acid

Structure of glycolic acid

Glycolic acid has been proven in independent scientific studies to do the following:

  • Stimulate collagen production (International Journal of Cosmetic Science, 1998).  While the glycolic acid used in this study was in extremely high concentration, it has been noted in other sources as well that lower strengths of glycolic acid can create smaller amounts of collagen stimulation (Dermatologic Surgery, 1998).
  • Increase skin thickness over time (Dermatologic Surgery, 2001).  Glycolic acid will stimulate the thickness of the outermost layer of skin by increasing collagen and hyaluronic acid production.
  • Decrease sunspots, solar lentigos, and other signs of hyperpigmentation (Experimental Dermatology, 2003).  A little known fact:  Like hyaluronic acid or resorcinol, glycolic acid will directly inhibit tyrosinase, an enzyme necessary for skin pigment (melanin) production.

The only thing about glycolic acid is that I prefer not to use it with retinoids.  In order to be active, retinol and retinyl palmitate must be converted to tretinoin in the skin.  This conversion step requires the activity of enzymes called retinyl ester hydrolases, which operate best at a pH of 4.5-7 (a neutral pH) (Biochim Biophys Acta, 2002).

So while I like both retinoids and glycolic acid, I agree with dermatologist Dr. Leslie Baumann, M.D., and conclude that retinoids and glycolic acids are best used on alternating nights.  I personally use retinoids nightly, and will switch to a product with glycolic acid, like Age Advantage Wrinkle Reduction Creme, once/week.  (Either that, or get a peel!)

Vitamin E, Alpha Lipoic Acid, and Ubiquinone

Food for Life distributes food on an internati...
Not all antioxidants are created equal. Some antioxidants essentially travel in the same networks, and can borrow electrons from one another to be recycled and reused again.

There are five network antioxidants I love to use together:

The reason?  These antioxidants are “network antioxidants,” which means that they can regenerate and enhance one another.

Let me explain further.  When an antioxidant encounters a free radical, it neutralizes it by donating an electron to the free radical.  Good times.  The only problem is, now the antioxidant is no longer active.  The antioxidant needs to be recycled.

The good news is, vitamin C and ubiquinone (coQ10) can recycle vitamin E, and vitamin C and alpha lipoic acid can recycle both vitamin C and glutathione (Cosmetic Dermatology, 2011).  This is because these antioxidants are acting on the same pathways within the cell.

So the fact that Age Advantage Wrinkle Reduction Creme contains three of the five gets me really excited.  And while vitamin C creams are a dime a dozen nowadays, the two that are the hardest to find – alpha lipoic acid and ubiquinone – are both in this cream.  (For the record, alpha lipoic acid and ubiquinone are hard to find because they’re also quite expensive to put in products, at least when compared to ingredients like vitamins C and E.  As a result, the $66.98 price tag on Age Advantage Wrinkle Reduction Creme is actually not that bad).

So while I never use a vitamin C and E serum at night, I will do so whenever I use Age Advantage Wrinkle Reduction Creme, just to be sure I get four of the five network antioxidants.  (Only glutathione is missing).  It’s pretty amazing.

Emu Oil and Ethoxydiglycol

English: An emu (Dromaius novaehollandiae) loo...
Emus are pretty cute. And emu oil has been found to be hydrating and to penetrate the skin fairly well, too, suggesting that it makes a fine delivery system for skin care creams.

The last selling point for me with Age Advantage Wrinkle Reduction Creme is that it contains a solid delivery system.  Emu oil is rare to find in skin care products, but it has been found to have better skin penetrating abilities than mineral oil (Australasian Journal of Dermatology, 2007).  The same study also suggested emu oil may also have more superior moisturizing ability than mineral oil, though the result was not statistically significant.

The skin also absorbs Age Advantage Wrinkle Reduction Creme well because of the ethoxydiglycol, which thins the solution somewhat.

Personal Use and Opinions

Age Advantage Wrinkle Reduction Creme is best for those with normal to dry skin.  It hydrates well and drinks into the skin easily.  It leaves skin feeling smooth.  My only qualm is that it has a very mild smell reminiscent of Play-Doh, but which is not so strong that it would stop me from using it.  I personally will use mine once/week in place of a retinol cream.

Bottom Line

I like Age Advantage Wrinkle Reduction Creme, and I’ll be using it once/week over my favorite CE serum at night!

Product Rating:  9.5/10

  • High or optimized concentration of key ingredients:  3/3
  • Unique formulation or new technology: 3/3
  • Value for the money:  3/3
  • Sunscreen: 0.5/1 (there is sunscreen as zinc oxide, but it is not quantified, hence 0.5)


Aloe Barbadensis Leaf Extract, Emu Oil (Dromiceius), Glycolic Acid, Glycerin, Cetearyl Alcohol, Ceteareth-20, Glyceryl Stearate, PEG-100 Stearate, Tocopherol (Vitamin E), Squalane, Thioctic Acid (Alpha Lipoic Acid), Dimethyl MEA, Hydrolyzed Elastin, Hydrolyzed Collagen, Acetyl Hexapeptide-9 (Argireline), Ubiquinone (Co-Enzyme Q-10), Allantoin, Panthenol, Dimethicone, Cyclomethicone, Retinyl Palmitate (Vitamin A), Zinc Oxide, Capryly Glycol, Ethoxydiglycol, Hippophea (Sea Buckthorn Oil), Phenoxethanol, Hexylene Glycol, Sodium Phytate.

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