Occasionally, a product comes along with a concept I adore. One such product is Priori Radical Defense ($120.00 retail, $110.00 on SkinCareRx.com). Named one of the 30 greatest beauty products of our time by the British Telegraph, Priori Radical Defense combines a potent dual chemical/physical broad-spectrum sunscreen of SPF 30 with antioxidant powerhouse idebenone in a side-by-side pump dispenser. Pretty clever, if I do say so myself.
Idebenone is an incredible antioxidant that is technically a stable analog of the antioxidant coenzyme Q10. Idebenone neutralizes free radicals and protects the skin from many UV-induced reactive oxidative species, according to the Journal of Cosmetic Dermatology. Idebenone use for six weeks was found in a 2005 double-blind study in the Journal of Cosmetic Dermatology to result in significant improvements in aging:Â in the study, forty-one female subjects, aged 30-65, with moderate photodamaged skin used creams with either 0.5% or 1.0% idebenone. After one-and-a-half months’ use of the 1.0% idebenone formula, a 26% reduction in skin roughness/dryness was observed, a 37% increase in skin hydration, a 29% reduction in fine lines/wrinkles, and a 33% improvement in overall global assessment of photodamaged skin. For the 0.5% idebenone formulation, a 23% reduction in skin roughness/dryness was observed, a 37% increase in skin hydration, a 27% reduction in fine lines/wrinkles, and a 30% improvement in overall global assessment of photodamaged skin.
In comparison with other antioxidants, idebenone is more effective at reducing oxidative stress than vitamin E, kinetin, ubiquinone, vitamin C, and lipoic acid, according to a 2007 study in the Journal of Cosmetic Dermatology, and is second in antioxidant protection only to antioxidant powerhouse coffeeberry, found in the Revale Skin line.
In comparison with the other most potent antioxidant-sunscreen combination product, Revale Skin SPF 30 with CoffeeBerry ($72.00, Amazon.com), Priori Radical Defense contains a far better sunscreen combination. While Revale Skin SPF 30 with CoffeeBerry only offers SPF 15 and standard UVA protection, Priori Radical Defense protects with physical sunscreen (zinc oxide 8%) that prevents UV rays from hitting the skin, as well as chemical sunscreens (octinoxate 7.5%, octisalate 5%, and oxybenzone 5%) to prevent contacted UV rays from damaging the skin.  Unfortunately, the idebenone in Priori Radical Defense is not as potent an antioxidant as the coffee berry in Revale Skin SPF 30 with CoffeeBerry, and some individuals (myself included) also experience sensitivity after idebenone use.
With that said, the following is the way I see it: If you are looking for potent antioxidant-sunscreen protection, and your skin is NOT sensitive, I say go with Priori Radical Defense, for the best sunscreen. However, if your skin IS sensitive, I say go with Revale Skin SPF 30 with CoffeeBerry. And because different antioxidants neutralize free radicals in different ways, it’s always a great idea to mix up the antioxidants you use. Try Priori Radical Defense during the day and Revale Skin Night Cream at night, OR Revale Skin SPF 30 with CoffeeBerry during the day and Priori Night Cream at night. No matter how you go, it’s a win-win! 🙂
Product rating: 9.5/10 (High concentration of effective ingredients: 3/3. Novel technology: 3/3. Value for the money: 2,5/3.  Sunscreen: 1/1).