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Photolyase is naturally found within the skin, but most assuredly deplete with age (Gerontology, 1991). Photolyase reverses DNA damage in cells and prevents cell death caused by UV exposure. It has been shown in trials to reduce UVB radiation-induced dimers by 45% and to increase UV protection by 300% (source). According to the text The New Science of Perfect Skin, liposome-encapsulated photolyase is delivered to the skin within an hour of application. It requires light for its activation, though any mild indoor light that passes through sunscreen should be enough for it to work properly.
As for whether or not the photolyase could potentially harm the cell’s DNA, I called in Dr. Helen Torok, M.D., a board-certified dermatologist for twenty-five years and the current Medical Director at Trillium Creek Dermatology in Medina, OH, who is familiar with the technology. Of potential damage to cellular DNA, she says, “We cannot say with complete certainty but most likely not. The DNA repair enzymes detect DNA damage, remove the damage and then assist the body’s own natural repair mechanisms in restoring healthy DNA. The body can do this on its own, but repeated sun exposure – whether or not a sunburn forms – lessens the skin’s ability to repair itself. The DNA repair enzymes help to promote the recovery process.”
As for products that contain photolyase, nearly all NEOVA products do. Visit our NEOVA page to view all of the products!